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Study identifier: NCT07637799 Synced from ClinicalTrials.gov · July 29, 2026
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Feasibility Study of UP-A-AST Parent Group for Adolescents With Autism and Co-occurring Anxiety/Depression

Condition: Autistic Spectrum Disorder · Anxiety Disorders · Depressive Disorder  ·  Sponsor: Sahlgrenska University Hospital

PhaseNA
Planned participants72
Who can joinAll sexes, 12 Years to no upper limit
Healthy volunteersNo

About this study

Autism spectrum disorder (ASD) is associated with high rates of psychiatric comorbidity, particularly anxiety and depressive disorders, which contribute to significant impairment for affected youth and their families. Although cognitive behavioral therapy (CBT) is recommended as a first-line treatment for anxiety and depression in children and adolescents, there is a lack of evidence-based interventions specifically adapted for youth with ASD and co-occurring emotional disorders. The Unified Protocol for Transdiagnostic Treatment of Emotional Disorders in Children and Adolescents (UP-C/UP-A) is a CBT-based intervention targeting shared mechanisms underlying anxiety and depression. A parent-mediated adaptation, the Unified Protocol-Adolescent Autism Parent Group (UP-A-AST), has been developed to address the specific needs of adolescents with ASD and co-occurring anxiety and/or depressive disorders. Preliminary quality improvement work has shown promising results. This study aims to evaluate the feasibility, acceptability, and preliminary effects of the UP-A-AST Parent Group in a child and adolescent outpatient psychiatric setting. The study will include parents of adolescents aged 12-17 years with ASD and co-occurring anxiety and/or depressive disorders. Outcomes include changes in adolescents' psychiatric symptoms and functional impairment, as well as parents' perceived parenting competence. Additionally, parents' experiences of participating in the intervention will be exp…

This description comes directly from the study's public registry record.

Talk to the study team

Karin Melin, PhD  ·  +46730494348  ·  karin.a.melin@vgregion.se

Sahlgrenska University Hospital  ·  +46313421000

Always discuss trial participation with your own doctor first.

Locations (1)

BUP- Specialmottagning, Sahlgrenska University HospitalGothenburg, SwedenRecruiting

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Source record: clinicaltrials.gov/study/NCT07637799