Condition: Ehlers-Danlos Syndrome, Hypermobile · Chronic Pain · Fatigue Syndrome, Chronic · Sponsor: Centre Medical ISM (Integrative Systemic Medicine)
This study evaluates the effect of photobiomodulation (PBM) therapy using a MLS® class IV laser on chronic pain and fatigue in patients with hypermobile Ehlers-Danlos Syndrome (hEDS). hEDS is a hereditary connective tissue disorder characterized by joint hypermobility, chronic pain, and debilitating fatigue, for which therapeutic options remain limited. Participants will receive 10 PBM sessions over 5 weeks (2 sessions per week), using red and near-infrared light (808 nm continuous + 905 nm pulsed) applied to painful areas identified at baseline. Pain (Visual Analogue Scale), multidimensional fatigue (MFI-20), and quality of life (EQ-5D-5L) will be assessed at baseline (T0), end of treatment (week 5), and follow-up (week 10). This is a pilot observational study - the first to document the effect of MLS® laser PBM in hEDS. No additional procedures beyond routine care are required.
This description comes directly from the study's public registry record.
Lilian Lessedjina, M.D. · +337-82-83-40-83 · dr.llessedjina@gmail.com
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| Centre Médical ISM | Boulogne-Billancourt, Île-de-France Region, France | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07637084