Condition: Malignant Neoplasm · Sponsor: Merck Sharp & Dohme LLC
Researchers are looking for new ways to treat children with relapsed or refractory solid tumors: * Relapsed means the cancer came back after treatment * Refractory means the cancer did not respond (get smaller or go away) to treatment * Solid tumors are cancers mostly in body organs and tissues, not in the blood or other body liquids The study treatment I-DXd (also known as MK-2400 or ifinatamab deruxtecan) is an antibody-drug conjugate (ADC). An ADC attaches to a protein on cancer cells and delivers treatment to destroy those cells. The goals of this study are to learn: * About the safety of I-DXd and if children younger than 12 years old tolerate it * How many children who receive I-DXd have the cancer get smaller or go away
This description comes directly from the study's public registry record.
Toll Free Number · 1-888-577-8839 · Trialsites@msd.com
Always discuss trial participation with your own doctor first.
| University of Iowa Hospitals ( Site 4017) | Iowa City, Iowa, United States | Recruiting |
| Dana Farber Cancer Center ( Site 4013) | Boston, Massachusetts, United States | Recruiting |
| Rutgers Cancer Institute of New Jersey ( Site 4008) | New Brunswick, New Jersey, United States | Recruiting |
| Memorial Sloan Kettering Cancer Center ( Site 4010) | New York, New York, United States | Recruiting |
| New York Medical College ( Site 4023) | Valhalla, New York, United States | Recruiting |
| Children's Hospital of Philadelphia (CHOP) ( Site 4021) | Philadelphia, Pennsylvania, United States | Recruiting |
| Intermountain - Primary Children's Hospital ( Site 4014) | Salt Lake City, Utah, United States | Recruiting |
| UZ Gent ( Site 4428) | Ghent, Oost-Vlaanderen, Belgium | Recruiting |
| Rigshospitalet ( Site 4467) | Copenhagen, Capital Region, Denmark | Recruiting |
| CENTRE LEON BERARD ( Site 4100) | Lyon, Rhone, France | Recruiting |
| Rambam Health Care Campus ( Site 4674) | Haifa, Israel | Recruiting |
| Seoul National University Hospital-Pediatrics ( Site 4972) | Seoul, South Korea | Recruiting |
+ 5 more locations — full list on the registry record.
Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.
We email about this public record only. Unsubscribe anytime with one click. Never medical advice.
This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.
Source record: clinicaltrials.gov/study/NCT07630974