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Study identifier: NCT07630961 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Phase I Study of JFI447 [68Ga]Ga-DFC413 and Comparison to FFG233 [68Ga]Ga-NNS309 in Patients With Solid Tumors

Condition: Metastatic Pancreatic Ductal Adenocarcinoma (PDAC) · Non-small Cell Lung Cancer (NSCLC) · HR+/HER2- Ductal Breast Cancer (BC)  ·  Sponsor: Novartis Pharmaceuticals

PhasePhase 1
Planned participants66
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of Part 1 of this study is to evaluate the imaging characteristics, safety, biodistribution and pharmacokinetics of \[68Ga\]Ga-DFC413, and in Part 2 compare to \[68Ga\]Ga-NNS309 in patients with locally advanced or metastatic pancreatic ductal adenocarcinoma (PDAC), non-small cell lung cancer (NSCLC), HR+/HER2- ductal and lobular breast cancer (BC), triple negative breast cancer (TNBC), colorectal cancer (CRC), and soft tissue sarcoma (STS). In Part 2 of this study (comparison of \[68Ga\]Ga-DFC413 and \[68Ga\]Ga-NNS309), not all indications might be explored.

This description comes directly from the study's public registry record.

Talk to the study team

Novartis Pharmaceuticals  ·  1-888-669-6682  ·  novartis.email@novartis.com

Novartis Pharmaceuticals  ·  +41613241111

Always discuss trial participation with your own doctor first.

Locations (1)

Novartis Investigative SiteChuo Ku, Tokyo, JapanRecruiting

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Source record: clinicaltrials.gov/study/NCT07630961