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Study identifier: NCT07630857 Synced from ClinicalTrials.gov · July 29, 2026
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Unipolar Voltage Mapping for Personalized Atrial Fibrillation Ablation

Condition: Atrial Fibrillation (AF)  ·  Sponsor: China National Center for Cardiovascular Diseases

PhaseNA
Planned participants200
Who can joinAll sexes, 18 Years to 80 Years
Healthy volunteersNo

About this study

Atrial fibrillation (AF) is a common heart rhythm disorder. While catheter ablation is an effective treatment, many patients still experience AF recurrence after the procedure. One major reason is that the mechanisms that maintain AF are not fully understood. Research suggests that the outer layer of the heart (epicardium) may play an important role in keeping AF going. However, current mapping techniques have limitations in detecting electrical signals from both the inner and outer heart layers. This study uses a different technique called unipolar voltage mapping, which may more accurately capture electrical signals from both heart layers. Specifically, we focus on a specific type of electrical signal called "QS potential" on unipolar mapping, which reflects breakthrough sites between the inner and outer heart layers. In this interventional study, participants with AF undergoing catheter ablation will receive personalized ablation guided by unipolar QS-potential mapping. We aim to: Explore the relationship between unipolar QS-potentials and AF maintenance and atrial remodeling Evaluate the effectiveness of QS-potential guided personalized AF ablation

This description comes directly from the study's public registry record.

Talk to the study team

AIJU TIAN  ·  +8618811592092  ·  taj2015@163.com

Always discuss trial participation with your own doctor first.

Locations (1)

Fuwai HospitalBeijing, Beijing Municipality, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07630857