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Study identifier: NCT07629440 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Study to Learn About How a New Pneumococcal Vaccine Works in Infants.

Condition: Pneumococcal Disease  ·  Sponsor: Pfizer

PhasePhase 3
Planned participants3230
Who can joinAll sexes, 42 Days to 211 Days
Healthy volunteersYes

About this study

The purpose of this study is to learn about the safety of a new pneumococcal vaccine and how the new pneumococcal vaccine helps to fight against germs that can cause pneumonia (lung infections), meningitis (brain infections), and otitis media (ear infections) in infants when compared to the pneumococcal vaccine that is currently in use, 20vPnC (Prevnar 20®). This study will test if the new pneumococcal vaccine is as safe as the one that is currently in use. It will also assess how the new vaccine works in comparison to the one that is currently in use when given with other childhood vaccines. To measure how the new pneumococcal vaccine compares to the current one, blood samples will be used to measure the body's ability to create proteins to fight those germs. This new vaccine can possibly provide additional protection against germs that cause pneumococcal disease that are not included in the vaccines that are currently given to infants. Pneumococcal disease includes a variety of infections caused by a specific germ, Streptococcus pneumoniae. There are three groups in this study. All participants will be assigned to one of the three groups. This study is seeking participants who are: * infants who are 2 months of age in Group 1; * infants who are 2 to 6 months of age in Groups 2 and 3; and * said to be healthy by the study doctor About 3000 infants will be assigned to Group 1. The infants in this group will have a 1 in 2 chance (50%) of receiving either PG4 (new vaccine)…

This description comes directly from the study's public registry record.

Talk to the study team

Pfizer CT.gov Call Center  ·  1-800-718-1021  ·  ClinicalTrials.gov_Inquiries@pfizer.com

Always discuss trial participation with your own doctor first.

Locations (97)

Alabama Clinical Therapeutics, LLC Birmingham Pediatric AssociatesBirmingham, Alabama, United StatesRecruiting
University of Alabama at Birmingham - School of MedicineBirmingham, Alabama, United StatesNot Yet Recruiting
KUR Research, LLCCentreville, Alabama, United StatesNot Yet Recruiting
Northwest Arkansas Pediatric ClinicFayetteville, Arkansas, United StatesRecruiting
The Children's Clinic of Jonesboro, P.A.Jonesboro, Arkansas, United StatesRecruiting
Helios Clinical ResearchSherwood, Arkansas, United StatesNot Yet Recruiting
San Gabriel Woman's HealthArcadia, California, United StatesRecruiting
Family Medical ClinicEl Monte, California, United StatesRecruiting
Clinical Research of Central CaliforniaFresno, California, United StatesRecruiting
SeraCollection Research Services, LLCMontebello, California, United StatesRecruiting
Bailony PediatricsNational City, California, United StatesNot Yet Recruiting
Stanford University Medical CenterPalo Alto, California, United StatesNot Yet Recruiting

+ 85 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07629440