Condition: Sepsis · Sponsor: University of British Columbia
This study is an observational multi-country cohort study that aims to build algorithms that can identify children between 5 and 16 years of age admitted for proven or suspected sepsis who are at risk of mortality after they are discharged in East Africa. In low- and middle-income countries, about 5% of children discharged after hospitalization for sepsis will die in the weeks after returning home. Doctors and parents are often unaware of this period of vulnerability and are poorly equipped to identify or handle this critical situation. This project builds on past work that developed and evaluated models and the Smart Discharges program to predict, during hospitalization, an individual child's risk of recurrent illness and mortality, as well as to provide additional post-discharge support to at-risk children. Participants will be enrolled from facilities once they are admitted, collecting clinical and social variables. They will then be followed until 6 months post-discharge to understand what happens to them after they return home. This data will be evaluated to identify which variables collected at facilities can be predictive of mortality and recurrent illness after discharge.
This description comes directly from the study's public registry record.
Matthew Wiens, PhD · 604-829-2562 · matthew.wiens@bcchr.ca
Always discuss trial participation with your own doctor first.
| University of California, San Francisco | San Francisco, California, United States | Not Yet Recruiting |
| Weill Cornell Medicine | Ithaca, New York, United States | Not Yet Recruiting |
| University of Washington | Seattle, Washington, United States | Not Yet Recruiting |
| BC Children's Hospital Research Institute | Vancouver, British Columbia, Canada | Active Not Recruiting |
| The Rwanda Paediatric Association | Kigali, Rwanda | Recruiting |
| Catholic University Of Health And Allied Sciences | Mwanza, Tanzania | Recruiting |
| WALIMU | Mbarara, Uganda | Completed |
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Source record: clinicaltrials.gov/study/NCT07629154