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Study identifier: NCT07628751 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Study of Standard Of Care Versus Radio Ablation in Early Stage HCC

Condition: Early Hepatocellular Carcinoma  ·  Sponsor: University Health Network, Toronto

PhaseNA
Planned participants218
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This Phase II Prospective, parallel and open-label randomised control trial will investigate whether a radiotherapy technique (called SABR) can treat early stage liver cancer more effectively than current treatments which use heating probes directly inserted into the tumour or chemotherapy or radioactive particles injected into the blood supply of the tumour. Investigators hypothesize SABR will result in higher rates of freedom from local progression (FFLP) at 2 years compared to percutaneous thermal ablation ± TACE or transarterial therapies (TACE/TARE).The study will also look at other important outcomes such as progression free survival, overall survival, side effects, quality of life and people's experiences of their treatment.

This description comes directly from the study's public registry record.

Talk to the study team

Michael Yan, MD MPH FRCPC DABR  ·  (416) 946-2320  ·  Michael.Yan@uhn.ca

Always discuss trial participation with your own doctor first.

Locations (2)

Trans Tasman Radiation Oncology GroupWaratah, AustraliaRecruiting
University Health Network - Princess Margaret Cancer CentreToronto, Ontario, CanadaRecruiting

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Source record: clinicaltrials.gov/study/NCT07628751