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Study identifier: NCT07627178 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Prospective Comparative Study Evaluating the Safety and Efficacy of Transurethral Thulium Fiber Laser, Holmium Laser and Bipolar Enucleation of Large Sized Prostate

Condition: Benign Prostatic Hyperplasia (BPH) · Lower Urinary Tract Symptom · Bladder Outlet Obstruction  ·  Sponsor: Tanta University

PhaseNA
Planned participants90
Who can joinMale, N/A to no upper limit
Healthy volunteersYes

About this study

This study compares the safety and efficacy of three endoscopic enucleation techniques for large prostates (\>100 mL) in patients with benign prostatic hyperplasia (BPH): Thulium Fiber Laser Enucleation (ThuFLEP), Holmium Laser Enucleation (HoLEP), and Bipolar Enucleation (B-TUEP). Ninety male patients with severe lower urinary tract symptoms (IPSS ≥20, Qmax ≤10 mL/s) who failed medical therapy will be randomized 1:1:1 into three groups of 30. Primary outcomes include IPSS, quality of life score, maximum flow rate (Qmax), and post-void residual at 1, 3, and 6 months postoperatively. Secondary outcomes include operative time, enucleation efficiency, blood loss, catheterization duration, hospital stay, and complication rates assessed by the Clavien-Dindo classification.

This description comes directly from the study's public registry record.

Talk to the study team

Abdullah Salah Al Debeiky, MD  ·  +201221430915  ·  abdullah.aldebeiky@med.tanta.edu.eg

Omar Khaled Gad, MSc  ·  +201117837272  ·  omar_khaled@med.tanta.edu.eg

Always discuss trial participation with your own doctor first.

Locations (1)

Tanta University HospitalTanta, Gharbia Governorate, EgyptRecruiting

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Source record: clinicaltrials.gov/study/NCT07627178