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Study identifier: NCT07626710 Synced from ClinicalTrials.gov · July 28, 2026
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Impact of Trans-catheter Aortic Valve Implantation on Renal Function

Condition: Aortic Valve Stenosis · Chronic Kidney Diseases · Renal Failure Acute Chronic  ·  Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS

PhaseN/A
Planned participants1000
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Both contrast-induced acute kidney injury (AKI) and pre-existing chronic kidney disease are associated with an increased mortality risk in patients requiring aortic valve replacement. Nonetheless, the direct haemodynamic impact of the aortic barrage (i.e. pre-renal mechanism) on renal function compromising and its reversibility in patients undergoing trans-catheter aortic valve implantation (TAVI) is unknown. This registry aims to evaluate the effect of severe aortic stenosis removal on the risk of contrast-induced acute renal injury (CI-AKI) during TAVI procedures and on renal function evolution

This description comes directly from the study's public registry record.

Talk to the study team

Enrico Romagnoli, MD, PhD  ·  +390630154187  ·  enromagnoli@gmail.com

Benedetta Brancadoro  ·  +390630154187  ·  benedetta.brancadoro@unicatt.it

Always discuss trial participation with your own doctor first.

Locations (1)

Enrico RomagnoliRoma, RM, ItalyRecruiting

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Source record: clinicaltrials.gov/study/NCT07626710