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Study identifier: NCT07625020 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Ultrasound-Guided Nerve Hydrodissection for Diabetic Lower Limb Entrapment Neuropathy

Condition: Diabetic Peripheral Neuropathy · Entrapment Neuropathy  ·  Sponsor: Chongqing Medical University

PhaseNA
Planned participants266
Who can joinAll sexes, 18 Years to 85 Years
Healthy volunteersNo

About this study

The goal of this clinical trial is to learn if a single session of ultrasound-guided nerve hydrodissection can relieve symptoms of diabetic lower limb entrapment neuropathy, a condition caused by compressed nerves in the leg that leads to numbness, pain, or muscle weakness in people with diabetes. The main questions it aims to answer are whether nerve hydrodissection improves nerve function (measured by the Toronto Clinical Scoring System) one month after treatment, and whether it relieves pain and improves quality of life. Researchers will compare two groups: one will receive the actual nerve hydrodissection (injection of medicine around the compressed nerve), and the other will receive a sham procedure that involves injecting a small amount of fluid under the skin (not around the nerve). Participants will not know which group they are in, and the researchers who measure the results will also not know. Participants will have four in-person visits over about one month, complete questionnaires about their nerve symptoms, pain, and quality of life, undergo nerve ultrasound at the beginning and at follow-up visits (at 1 month after treatment), and receive either the nerve hydrodissection or the sham procedure at the second visit. All participants will continue their regular diabetes and nerve medication during the study.

This description comes directly from the study's public registry record.

Talk to the study team

Qingfeng Cheng, PhD  ·  13628482293  ·  cqf19760516@163.com

Always discuss trial participation with your own doctor first.

Locations (1)

The First Affiliated Hospital of Chongqing Medical UniversityChongqing, Chongqing Municipality, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07625020