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Study identifier: NCT07623382 Synced from ClinicalTrials.gov · July 29, 2026
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Human Umbilical Cord Mesenchymal Stem Cell-derived Small Extracellular Vesicles for the Treatment of Dry Eye Disease

Condition: Dry Eye Disease · Umbilical Cord Mesenchymal Stem Cell-derived Small Extracellular Vesicles  ·  Sponsor: The First Affiliated Hospital of Xiamen University

PhaseEARLY_Phase 1
Planned participants20
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This clinical trial aims to preliminarily evaluate the safety and efficacy of human umbilical cord mesenchymal stem cell small extracellular vesicle eye drops in patients with dry eye disease. 1. Human mesenchymal stem cell small extracellular vesicle eye drops: Administer one drop each time, 4 times daily, for a treatment duration of 4 weeks. 2. During treatment, subjects will be followed up and undergo examinations and related tests weekly. 3. After completion of treatment, follow-up visits will be conducted every 2 weeks for a total of 2 visits. 4. Subsequently, subjects will enter a long-term follow-up period, with follow-up assessments at 3 months and 6 months to observe longer-term safety and efficacy. 5. Subjects shall record medication usage and any possible adverse reactions.

This description comes directly from the study's public registry record.

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Locations (1)

The First Affiliated Hospital of Xiamen UniversityXiamen, China, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07623382