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Study identifier: NCT07623161 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Study to Compare Elritercept to Placebo in Adults With Myelofibrosis and Anemia Who Are Taking Ruxolitinib

Condition: Myelofibrosis · Anemia  ·  Sponsor: Takeda

PhasePhase 3
Planned participants324
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The main aim of this study is to find out how well elritercept works to improve anemia in participants with myelofibrosis (MF) who are taking ruxolitinib when compared to placebo. Other aims are to learn how elritercept improves anemia compared to placebo; to learn if elritercept reduces tiredness, improves symptoms related to MF, and helps participants do physical activities more easily. The study also aims to find out how elritercept affects the bone marrow, the spleen, and whether participants develop antibodies to the study drug. The study will also check how safe elritercept is compared to placebo, and if elritercept stays safe over a long period of time. Participants will receive study treatment for at least 9 months (36 weeks). After this period, participants who received placebo will have the option to switch to elritercept.

This description comes directly from the study's public registry record.

Talk to the study team

Takeda Contact  ·  +1-877-825-3327  ·  medinfoUS@takeda.com

Always discuss trial participation with your own doctor first.

Locations (207)

Los Angeles Cancer NetworkGlendale, California, United StatesNot Yet Recruiting
Cancer and Blood Specialty ClinicWhittier, California, United StatesNot Yet Recruiting
MedStar Georgetown University HospitalWashington D.C., District of Columbia, United StatesNot Yet Recruiting
Advanced Research, LLCCoral Springs, Florida, United StatesNot Yet Recruiting
Bioresearch PartnersMiami, Florida, United StatesNot Yet Recruiting
AdventHealth - Cancer Institute - OrlandoOrlando, Florida, United StatesNot Yet Recruiting
Florida Clinical Trials GroupTamarac, Florida, United StatesNot Yet Recruiting
Moffit Cancer CenterTampa, Florida, United StatesNot Yet Recruiting
Emory UniversityAtlanta, Georgia, United StatesNot Yet Recruiting
Tufts Medical CenterBoston, Massachusetts, United StatesNot Yet Recruiting
University of MichiganAnn Arbor, Michigan, United StatesNot Yet Recruiting
Washington University School of MedicineSt Louis, Missouri, United StatesNot Yet Recruiting

+ 195 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07623161