Condition: Energy Balance · Physiology - Regulation of Appetite and Food Intake · Sponsor: Wilfrid Laurier University
The goal of this study is to determine if estradiol and progesterone are involved in appetite regulation and energy balance. The study aims to complete a 13 day randomized controlled trial (RCT) where oral supplementation of estradiol only, progesterone only, a combination of each, or a placebo in young males will be provided. During the supplementation period, participants will complete two in-lab sessions where they will complete an acute bout of high-intensity interval training or a period of seated rest (completed on separate days by each participant) and have blood samples and perceptions of appetite measured taken over the course of the in-lab sessions. At the end of each session participants will consume an ad-libitum meal and participants will also track free-living energy intake and wear a thigh-worn accelerometer to measure energy expenditure for three days (day before, day of, and day after) each in-lab session.
This description comes directly from the study's public registry record.
Jessica Tucker, MKin, PhD Candidate · 519-884-1970 · tuck5010@mylaurier.ca
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| Energy Metabolism Research Laboratory | Waterloo, Ontario, Canada | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07620587