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Study identifier: NCT07617805 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

EGFR/HER2 Dual-Target CAR-NK Cells for Recurrent or Metastatic HNSCC

Condition: Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma · Biomarker-positive EGFR/HER2- Expressing HNSCC  ·  Sponsor: Beijing Biotech

PhasePhase 1/Phase 2
Planned participants42
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

This example Phase 1/2 protocol evaluates allogeneic EGFR/HER2 dual-target CAR-NK cells in adults with recurrent or metastatic HNSCC whose tumors meet protocol-defined co-expression criteria for EGFR and HER2/ERBB2. The study is designed as a biomarker-enriched, open-label, non-randomized trial with a dose-escalation safety lead-in followed by an expansion cohort at the recommended Phase 2 dose (RP2D).

This description comes directly from the study's public registry record.

Talk to the study team

shan S Lu, Phd  ·  +86 13076790030  ·  Seni-Lu@beijing-biotech.com

Always discuss trial participation with your own doctor first.

Locations (1)

Peking University Shenzhen HospitalShenzhen, Guangdong, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07617805