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Study identifier: NCT07616999 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A 20-Year Follow-up of First Episode Psychosis: Longitudinal Effects of Early Treatment Strategies and Relapse

Condition: Schizophrenia  ·  Sponsor: The University of Hong Kong

PhaseN/A
Planned participants178
Who can joinAll sexes, 18 Years to 65 Years
Healthy volunteersNo

About this study

The study aims to address the following questions: 1. Do subgroups defined by early medication choices, relapse, and medication taken over 20 years differ in clinical, cognitive, and functional outcomes? 2. What are the long-term cognitive functioning trajectories, what factors predict these trajectories, and how do they relate to outcomes? 3. What might be the mechanisms behind medication discontinuation and poor long-term outcome, including the roles of multiple relapses and treatment resistance after first-episode psychosis? Eligible patients will be invited to a one-time face-to-face interview. A trained research assistant will guide the participants through questions about their background, clinical symptoms, daily functioning, cognitive abilities, and psychological well-being.

This description comes directly from the study's public registry record.

Talk to the study team

Lai Ming Christy Hui, PhD  ·  852-22554486  ·  christy@lmhui.com

Always discuss trial participation with your own doctor first.

Locations (1)

Department of Psychiatry, Queen Mary HospitalHong Kong, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07616999