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Study identifier: NCT07615348 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

CD70-Targeted Immuno-PET/CT-Directed Free of Therapy Used for mccRCC Patients With IMDC Favorable or Intermediate Risk

Condition: Metastatic Clear Cell Renal Cell Carcinoma  ·  Sponsor: Jinling Hospital, China

PhasePhase 2
Planned participants75
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this study is to evaluate the safety and feasibility of a treatment holiday strategy directed by CD70-targeted immuno-PET/CT in patients with metastatic clear cell renal cell carcinoma (mccRCC). Specifically, the study aims to assess whether patients who achieve both anatomical disease control and metabolic response after 12 months of first-line PD-1/PD-L1 ICI + VEGFR-TKI combination therapy can safely pause their treatment, improve quality of life without compromising therapeutic efficacy.

This description comes directly from the study's public registry record.

Talk to the study team

Le Qu, Ph.D.  ·  +86 15720625951  ·  septsoul@hotmail.com

Always discuss trial participation with your own doctor first.

Locations (5)

Jinling Hospital, Affiliated Hospital of Medical School, Nanjing UniversityNanjing, Jiangsu, ChinaRecruiting
Nanjing First Hospital, Nanjing Medical UniversityNanjing, Jiangsu, ChinaRecruiting
The First Affiliated Hospital of Nanjing Medical UniversityNanjing, Jiangsu, ChinaRecruiting
Sir Run Run Hospital, Nanjing Medical UniversityNanjing, Jiangsu, ChinaRecruiting
Wuxi No.2 People's Hospital (Jiangnan University Medical Center)Wuxi, Jiangsu, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07615348