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Study identifier: NCT07614984 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Clinical Trial of MK-7262 and Enlicitide in Participants With High Lipoprotein(a) (MK-7262-004)

Condition: Lipoprotein(a)  ·  Sponsor: Merck Sharp & Dohme LLC

PhasePhase 2
Planned participants750
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Researchers designed a trial medicine called MK-7262 to lower levels of Lp(a) in the blood. Researchers want to learn about giving MK-7262 with another trial medicine called enlicitide (also known as MK-0616 or enlicitide decanoate). Enlicitide is in a group of medicines that lower the amount of low-density lipoprotein cholesterol (LDL-C). The goals of this trial are to evaluate: * if MK-7262 and enlicitide taken together work better than placebo at lowering Lp(a) and LDL-C levels in the blood * if MK-7262 alone works better than placebo at lowering Lp(a) levels in the blood * the safety and tolerability of taking MK-7262 and enlicitide alone and together

This description comes directly from the study's public registry record.

Talk to the study team

Toll Free Number  ·  1-888-577-8839  ·  Trialsites@merck.com

Always discuss trial participation with your own doctor first.

Locations (12)

Advanced Cardiovascular - Alexander City ( Site 0158)Alexander City, Alabama, United StatesRecruiting
AMR Clinical Mobile ( Site 0149)Mobile, Alabama, United StatesRecruiting
National Heart Institute ( Site 0113)Beverly Hills, California, United StatesRecruiting
Clinical Trials Research ( Site 0127)Lincoln, California, United StatesRecruiting
Chase Medical Research, LLC ( Site 0163)Waterbury, Connecticut, United StatesRecruiting
Inpatient Research Clinic ( Site 0110)Miami Lakes, Florida, United StatesRecruiting
Clinical Research Trials of Florida ( Site 0101)Tampa, Florida, United StatesRecruiting
Conquest Research LLC ( Site 0140)Winter Park, Florida, United StatesRecruiting
New Mexico Clinical Research & Osteoporosis Center ( Site 0119)Albuquerque, New Mexico, United StatesRecruiting
Remington-Davis, Inc. ( Site 0107)Columbus, Ohio, United StatesRecruiting
Holston Medical Group ( Site 0117)Kingsport, Tennessee, United StatesRecruiting
Carient Heart & Vascular - Manassas ( Site 0165)Manassas, Virginia, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07614984