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Study identifier: NCT07614477 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of EVER001 in Participants With Selected Proteinuric Glomerular Diseases

Condition: Minimal Change Disease (MCD) · IgA Nephropathy (IgAN) · Focal Segmental Glomerulosclerosis (FSGS)  ·  Sponsor: Everest Medicines (China) Co.,Ltd.

PhasePhase 2
Planned participants45
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

This is a Phase 1b/2, open-label, multi-center study evaluating the therapeutic potential and safety of the investigational drug EVER001 in adults with FSGS, MCD, or IgAN. EVER001 acts on multiple immune pathways without directly affecting T cells or depleting B cells (both are lymphocytes). The study will be conducted at \~30 centers in China, enrolling 45 participants aged 18-75 years (15 per indication). The IMP is a 100 mg oral capsule, dosed at 200 mg twice daily (2 capsules per dose, 4 daily) for 52 weeks.

This description comes directly from the study's public registry record.

Talk to the study team

Fei Liao  ·  +8621- 8012 5712  ·  fei.liao@everestmedicines.com

Always discuss trial participation with your own doctor first.

Locations (2)

Peking University First HospitalBeijing, Beijing Municipality, ChinaRecruiting
Tianjin Medical University General HospitalTianjin, Hebei, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07614477