Condition: Obesity & Overweight · Lumbar Spine Surgery · Sponsor: Ataturk University
This randomized, single-center, single-masked clinical trial aims to compare the immunomodulatory effects of sevoflurane-based inhalational anesthesia and propofol-based total intravenous anesthesia in obese patients undergoing elective lumbar instrumentation surgery. Seventy patients will be randomized into two groups: a propofol group and a sevoflurane group. Blood samples will be collected preoperatively, at postoperative 6 hours, and at postoperative 24 hours. Pentraxin-3 and serum amyloid A levels will be evaluated as primary inflammatory biomarkers together with IL-6, TNF-α, CRP, glucose, and complete blood count parameters.
This description comes directly from the study's public registry record.
Mehmet Akif Yilmaz, Doctor · +905346533539 · mehmetakifyilmaz025@gmail.com
Ayşe Ceren Hilal Güven, assistant doctor · 554-112-25-81 · achg1995@gmail.com
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| Ataturk University | Erzurum, Turkey (Türkiye) | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07611240