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Study identifier: NCT07610798 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Antitumor Activity of INV-8989 in Patients With Advanced Solid Tumors Harboring KRAS G12D Mutations

Condition: Advance Solid Tumors · Colon and Rectal Cancer · Non - Small Cell Lung Cancer NSCLC  ·  Sponsor: Shenzhen Ionova Life Sciences Co., Ltd.

PhasePhase 1/Phase 2
Planned participants178
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a Phase 1 and Phase 2 study to evaluate the safety, tolerability, pharmacokinetics, and preliminary antitumor activity of INV-8989 in patients with advanced solid tumors harboring KRAS G12D mutations.

This description comes directly from the study's public registry record.

Talk to the study team

Yi Zhu, MD, MBA  ·  1 908 240 7514  ·  yi.zhu@ionovabio.com

Always discuss trial participation with your own doctor first.

Locations (1)

Sun Yat-sen University Cancer CenterGuangzhou, Guangdong, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07610798