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Study identifier: NCT07610590 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

guideSEQ: Genomic Understanding, Impact, Decision & Ethics in Prenatal Sequencing

Condition: Prenatal Genetic Diagnosis  ·  Sponsor: Columbia University

PhaseNA
Planned participants1042
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersYes

About this study

This study looks at whether genome sequencing should be used more routinely during pregnancy, even when ultrasounds look normal. Genome sequencing can examine nearly all of a baby's genes and may find genetic conditions that standard tests do not detect. Researchers will compare this test with current prenatal testing to see if it provides helpful information for families and doctors. The study will also explore how parents decide what kinds of genetic information they want to receive and how this information affects their experience during pregnancy. The goal is to understand whether genome sequencing can be used in a way that is helpful, responsible, and supportive for families in the future.

This description comes directly from the study's public registry record.

Talk to the study team

Camila Zarate, MPH  ·  646-300-0197  ·  cz2888@cumc.columbia.edu

Jessica Giordano, MS, CGC  ·  516-521-5604  ·  jlg2197@cumc.columbia.edu

Always discuss trial participation with your own doctor first.

Locations (3)

Boston Childrens HospitalBoston, Massachusetts, United StatesActive Not Recruiting
New York Genome CenterNew York, New York, United StatesActive Not Recruiting
Columbia University Irving Medical Center (CUIMC)New York, New York, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07610590