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Study identifier: NCT07608003 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Multicenter Prospective Study on MRI AI Model for Midline Glioma Subtyping and Prognosis:

Condition: Gliomas Harboring IDH1 and/or IDH2 Mutations · Glioma Glioblastoma Multiforme · Glioma of Brainstem  ·  Sponsor: Xiangya Hospital of Central South University

PhaseN/A
Planned participants500
Who can joinAll sexes, N/A to no upper limit
Healthy volunteersNo

About this study

A vision-language model using preoperative MRI and clinical variables has been developed to simultaneously predict three key molecular markers in midline gliomas: H3K27M, IDH, and 1p/19q. This prospective multicenter study will validate the model's accuracy in preoperative molecular subtyping and its value in prognostic assessment and clinical decision-making across multiple neurosurgical centers.

This description comes directly from the study's public registry record.

Talk to the study team

Gong Xuan, MD.  ·  0086-731-8975-3037  ·  gong.xuan@csu.edu.cn

Shuwen Kuang, MD.  ·  0086-13367494221  ·  228102171@csu.edu.cn

Always discuss trial participation with your own doctor first.

Locations (1)

Xiangya Hospital of Central South UniversityChangsha, Hunan, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07608003