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Study identifier: NCT07607418 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Ivosidenib as Maintenance Therapy in Transplant-Ineligible IDH1-mutated AML and HR-MDS

Condition: AML (Acute Myeloid Leukemia) · MDS (Myelodysplastic Syndrome)  ·  Sponsor: Ruijin Hospital

PhasePhase 2
Planned participants20
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This study will explore the efficacy and safety of ivosidenib as maintenance therapy in patients with IDH1-mutated AML and high-risk MDS who are ineligible for transplantation, along with accompanying molecular biomarker research. Patients who meet the eligibility criteria will receive ivosidenib treatment until disease progression or unacceptable toxicity. This study will provide an effective maintenance treatment option for transplant-ineligible patients with IDH1-mutated AML and high-risk MDS.

This description comes directly from the study's public registry record.

Talk to the study team

Sujiang Zhang  ·  86-21-64370045 ext 788755  ·  zbruce.zhang@hotmail.com

Always discuss trial participation with your own doctor first.

Locations (1)

Ruijin HospitalShanghai, Shanghai Municipality, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07607418