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Study identifier: NCT07606404 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Full-Thickness Macular Hole Surgery: A Comparison of Ten Techniques

Condition: Macular Holes  ·  Sponsor: Kazakh Eye Research Institute

PhaseNA
Planned participants120
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This study compares ten modern vitreoretinal surgical techniques for full-thickness macular hole repair. Participants will be randomly assigned to one of the surgical approaches during pars plana vitrectomy, using stratified randomization based on macular hole size to ensure balanced groups. The main goal is to determine which technique provides the highest anatomical closure rate on optical coherence tomography (OCT) and the best visual outcomes. Follow-up visits are scheduled at Day 7, Month 1, and Year 1 after surgery to assess OCT findings, visual acuity, safety outcomes, and the need for reoperation.

This description comes directly from the study's public registry record.

Talk to the study team

Sanzhar Sambet, MD  ·  +77758719834  ·  sanzhrs@gmail.com

Kairat Ruslanuly, MD  ·  +77019008387  ·  ruslanuly.kairat@gmail.com

Always discuss trial participation with your own doctor first.

Locations (1)

Kazakh Eye Research InstituteAlmaty, Almaty, KazakhstanRecruiting

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Source record: clinicaltrials.gov/study/NCT07606404