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Study identifier: NCT07605728 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Probiotics for Abemaciclib-Induced Abdominal Discomfort.

Condition: Breast Cancer · Chemotherapy-induced Diarrhea  ·  Sponsor: Leeuwenhoek Laboratories Co. Ltd.

PhasePhase 2
Planned participants80
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This study aims to evaluate whether the addition of probiotics can help reduce abdominal discomfort (such as diarrhea) in breast cancer patients receiving Abemaciclib treatment. Abemaciclib is an effective targeted therapy but often causes gastrointestinal side effects. While Loperamide is the standard treatment for diarrhea, this study explores if probiotics can provide additional relief and improve metabolic health.Participants will be randomly assigned to receive either probiotics or a placebo alongside their standard care. The study will monitor the frequency of abdominal symptoms and analyze blood samples to observe changes in metabolic factors.

This description comes directly from the study's public registry record.

Talk to the study team

Chiao-Wei Lin  ·  +886-2-2377-2318  ·  cwlin@lwhklab.com.tw

Always discuss trial participation with your own doctor first.

Locations (1)

National Taiwan University HospitalTaipei, TaiwanRecruiting

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Source record: clinicaltrials.gov/study/NCT07605728