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Study identifier: NCT07604987 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

R-PMDT Regimen in Newly Diagnosed PCNSL

Condition: Primary Central Nervous System (CNS) Lymphoma  ·  Sponsor: Zou Dehui

PhasePhase 2
Planned participants33
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

A total of six cycles of the R-PMDT regimen (rituximab, pirtobrutinib, high-dose methotrexate, dexamethasone, and thiotepa) will be administered to patients with newly diagnosed primary central nervous system lymphoma (PCNSL). The primary objective is to assess the overall response rate (ORR) of R-PMDT. Secondary objectives include evaluating the complete response rate, progression-free survival (PFS), overall survival (OS), and safety.

This description comes directly from the study's public registry record.

Talk to the study team

Wei Liu, Docter  ·  86-022-23608461  ·  liuwei@ihcams.ac.cn

Dehui Zou, Docter

Always discuss trial participation with your own doctor first.

Locations (1)

Institute of Hematology & Blood Diseases HospitalTianjin, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07604987