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Study identifier: NCT07604974 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Study to Assess the Safety, Tolerability and Efficacy of ION775

Condition: Hypertriglyceridemia · Severe Hypertriglyceridemia  ·  Sponsor: Ionis Pharmaceuticals, Inc.

PhasePhase 2
Planned participants72
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The main objective of this study is to evaluate the effect of ION775 on fasting triglyceride (TG) levels in participants with hypertriglyceridemia (HTG) and severe hypertriglyceridemia (sHTG).

This description comes directly from the study's public registry record.

Talk to the study team

Ionis Pharmaceuticals, Inc.  ·  1-844-828-3770  ·  IonisION775-CS2@clinicaltrialmedia.com

Always discuss trial participation with your own doctor first.

Locations (16)

Ionis Investigative SiteLincoln, California, United StatesRecruiting
Ionis Investigative SiteAurora, Colorado, United StatesRecruiting
Ionis Investigative SiteBoca Raton, Florida, United StatesRecruiting
Ionis Investigative SiteMiami, Florida, United StatesRecruiting
Ionis Investigative SiteMiramar, Florida, United StatesRecruiting
Ionis Investigative SiteColumbus, Georgia, United StatesRecruiting
Ionis Investigative SiteLouisville, Kentucky, United StatesRecruiting
Ionis Investigative SiteFlint, Michigan, United StatesRecruiting
Ionis Investigative SiteMunroe Falls, Ohio, United StatesRecruiting
Ionis Investigative SiteLittle River, South Carolina, United StatesRecruiting
Ionis Investigative SiteHouston, Texas, United StatesRecruiting
Ionis Investigative SiteLampasas, Texas, United StatesRecruiting

+ 4 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07604974