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Study identifier: NCT07604103 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Analysis of Growth Differentiation Factor 15 (GDF-15), Mid Regional proAdrenomedullin (MR proADM), and Persepsin Levels in Patient in Acute Coronary Syndrome Patients With Pneumonia, With or Without Influenza Vaccination

Condition: Acute Coronary Syndromes (ACS) · Pneumonia · COPD (Chronic Obstructive Pulmonary Disease)  ·  Sponsor: University of Brawijaya

PhasePhase 3
Planned participants60
Who can joinAll sexes, 18 Years to 65 Years
Healthy volunteersNo

About this study

The goal of this observational study is to analyze the relationship between various biomarkers (GDF-15, MR proADM, and Presepsin) in patients with Acute Coronary Syndrome (ACS) who also have Pneumonia and Chronic Obstructive Pulmonary Disease (COPD) and have received Influenza vaccinations. The main questions it aims to answer are: * Is there a significant correlation between the levels of these specific biomarkers and the clinical outcomes or inflammatory status of these patients? * How does Influenza vaccinations relate to the levels of these biomarkers in the context of ACS with comorbid respiratory conditions? Researchers will compare the levels of these biomarkers across the participant group to see if they can serve as indicators of the patients' health status or the impact of the vaccinations. Participants will: \- Undergo clinical assessment for Acute Coronary Syndrome, Pneumonia, and COPD. Provide medical history regarding Influenza vaccination status. Provide blood samples for the measurement of GDF-15, MR proADM, and Presepsin levels.

This description comes directly from the study's public registry record.

Talk to the study team

Martha FA Tatodi, MD  ·  +62895633927741  ·  3downdoomdrop@gmail.com

Rizky Tania Fadillah, MD  ·  +6281335808012

Always discuss trial participation with your own doctor first.

Locations (1)

RSUD Dr. Saiful AnwarMalang, East Java, IndonesiaRecruiting

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Source record: clinicaltrials.gov/study/NCT07604103