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Study identifier: NCT07603934 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

The Effect of Different Intra-canal Medications on Postoperative Pain

Condition: Pulp Necrosis, Apical Periodontitis  ·  Sponsor: Cairo University

PhaseEARLY_Phase 1
Planned participants111
Who can joinAll sexes, 18 Years to 40 Years
Healthy volunteersYes

About this study

The aim of this study is to assess the effect of ibuprofen, nitrofurantoin, and calcium hydroxide on postoperative pain after endodontic treatment of necrotic mandibular posterior teeth Research question/hypothesis: In patients with necrotic pulps in their mandibular posterior teeth, there would be no difference in the incidence and/or severity of postoperative pain after the use of ibuprofen, nitrofurantoin, or calcium hydroxide intracanal medications. The study will evaluate postoperative pain after using either of the tested drugs as an intracanal medication amidst visits. of endodontic treatment in cases where pulp necrosis is confirmed.

This description comes directly from the study's public registry record.

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Locations (1)

Faculty of Oral and Dental Medicine, Egyptian Russian UniversityCairo, Cairo Governorate, EgyptRecruiting

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Source record: clinicaltrials.gov/study/NCT07603934