Condition: Total Knee Arthroplasty Recovery · Sponsor: Lahore University of Biological and Applied Sciences
Total knee arthroplasty (TKA) is a commonly performed procedure for advanced knee osteoarthritis. Despite successful surgery, many patients experience postoperative impairments including pain, reduced range of motion (ROM), swelling, impaired proprioception, and kinesiophobia, which may delay functional recovery. Conventional physiotherapy is the standard rehabilitation approach following TKA; however, high-load strengthening exercises are often limited in the early postoperative phase due to pain and reduced tolerance. Blood flow restriction (BFR) exercise is an emerging rehabilitation technique that enables low-load exercise to produce strength adaptations similar to high-intensity training. While evidence supports its effectiveness for improving muscle strength, its effects on other outcomes such as pain, swelling, proprioception, and kinesiophobia are not well established. This randomized controlled trial will compare progressive BFR exercise combined with conventional physiotherapy versus conventional physiotherapy alone in patients following unilateral TKA. A total of 48 participants will be randomly allocated to two groups. The intervention will be delivered over 6 weeks with supervised sessions conducted three times per week. Outcomes will include pain, knee ROM, swelling, proprioception, kinesiophobia, and functional performance. This study aims to determine whether BFR exercise provides additional benefits in postoperative rehabilitation following TKA.
This description comes directly from the study's public registry record.
Umber Nawaz · +92 333 4888279 · Umber.nawaz@ubas.edu.pk
Shoaib Waqas · +92 302 4552109 · Shoaib.waqas@ubas.edu.pk
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| Saleem Memorial Trust Hospital | Lahore, Punjab Province, Pakistan | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07601906