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Study identifier: NCT07601867 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Effect of Dapagliflozin on Right Ventricular-Pulmonary Artery Coupling After Off-Pump Coronary Atery Bypass Grafting

Condition: Heart Failure · Coronary Arterial Disease  ·  Sponsor: Pyatigorsk City Clinical Hospital Number 1

PhaseN/A
Planned participants72
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This prospective, single-center observational study evaluates the effect of dapagliflozin 10 mg/day on right ventricular-pulmonary artery coupling measured by the TAPSE/PASP ratio in 72 patients with left ventricular ejection fraction \<50% after off-pump coronary artery bypass grafting (OPCAB). The primary outcome is the change in TAPSE/PASP ratio from 1 month after surgery (before dapagliflozin) to 7 months after surgery (after 6 months of dapagliflozin therapy).

This description comes directly from the study's public registry record.

Talk to the study team

Samson S. Badalyan, MD, PhD  ·  +79614972949  ·  sambadalyan@mail.ru

Syune V. Markosyan, MD.  ·  +79633876510  ·  ssm8883@gmail.com

Always discuss trial participation with your own doctor first.

Locations (1)

Pyatigorsk City Clinical Hospital Number 1Pyatigorsk, Stavropol Kray, RussiaRecruiting

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Source record: clinicaltrials.gov/study/NCT07601867