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Study identifier: NCT07601737 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Nimotuzumab Combined With Immunotherapy and Chemotherapy in the Treatment of Locally Advanced Head and Neck Squamous Cell Carcinoma

Condition: Head and Neck Squamous Cell Carcinoma · Head and Neck Squamous Cell Carcinoma (HNSCC) · Head & Neck Cancer  ·  Sponsor: Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine

PhasePhase 2
Planned participants182
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

This is a randomized controlled, phase II clinical study designed to explore the efficacy and safety of nimotuzumab combined with immunotherapy and chemotherapy as neoadjuvant treatment for locally advanced head and neck squamous cell carcinoma (LA-HNSCC). The primary endpoint of the study is the 2-year event-free survival (EFS) rate. Enrollment is expected to be completed within 2 years; all patients will be followed up for at least 2 years after the last patient is enrolled.

This description comes directly from the study's public registry record.

Talk to the study team

xin wei chen  ·  86+18616017916  ·  xinwei.chen@shgh.com

Always discuss trial participation with your own doctor first.

Locations (1)

Shanghai First People's HospitalShanghai, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07601737