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Study identifier: NCT07599657 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Surfactant Protein D Levels in GCF Before and After MINST in Periodontitis

Condition: Periodontitis · Periodontitis Stage II · Periodontitis Stage III  ·  Sponsor: Cairo University

PhaseNA
Planned participants18
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This study will evaluate changes in Surfactant Protein D (SP-D) levels in gingival crevicular fluid (GCF) of patients with periodontitis before and after minimally invasive non-surgical periodontal therapy (MINST). Participants diagnosed with stage II or III periodontitis will receive minimally invasive non-surgical periodontal treatment. GCF samples will be collected at baseline and 6 months after treatment, and SP-D levels will be measured using enzyme-linked immunosorbent assay (ELISA). The study will also assess clinical periodontal outcomes, including full-mouth plaque score, full-mouth bleeding score, probing pocket depth, clinical attachment level, gingival recession, and patient satisfaction. Each participant will serve as their own control by comparing baseline values with 6-month post-treatment values.

This description comes directly from the study's public registry record.

Talk to the study team

Hossam Ashraf ElMasry  ·  +201129559757  ·  hossam.eldamarany@dentistry.cu.edu.eg

Always discuss trial participation with your own doctor first.

Locations (1)

Faculty of Dentistry, Cairo UniversityCairo, EgyptRecruiting

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Source record: clinicaltrials.gov/study/NCT07599657