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Study identifier: NCT07599176 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Partial Stem Cell Transplant for Sickle Cell Disease From Matched Donors

Condition: Sickle Cell Disease · Beta-thalassemia  ·  Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

PhasePhase 1/Phase 2
Planned participants90
Who can joinAll sexes, 4 Years to 65 Years
Healthy volunteersNo

About this study

This is a non-ablative (partial) stem cell transplant for patients with severe sickle cell disease or beta-thalassemia requiring red cell transfusions. The intensity of the transplant is slightly increased from our previous transplant regimens. The goal is to aim for higher percentage of donor cells to stably remain in the recipients long term.

This description comes directly from the study's public registry record.

Talk to the study team

Kelly S Norris, R.N.  ·  (301) 529-7104  ·  kelly.norris@nih.gov

John F Tisdale, M.D.  ·  (301) 402-6497  ·  johntis@mail.nih.gov

Always discuss trial participation with your own doctor first.

Locations (1)

National Institutes of Health Clinical CenterBethesda, Maryland, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07599176