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Study identifier: NCT07598474 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Pregabalin Phonophoresis and MET for Knee Osteoarthritis

Condition: Knee Osteoarthritis  ·  Sponsor: University of Faisalabad

PhaseNA
Planned participants35
Who can joinAll sexes, 40 Years to 60 Years
Healthy volunteersNo

About this study

Knee osteoarthritis (OA) is a common condition causing pain, stiffness, and difficulty walking. Many patients with advanced (Grade III) knee OA also experience neuropathic pain - burning, tingling, or electric shock sensations - which is harder to treat with standard physiotherapy. Oral pregabalin works for neuropathic pain but causes side effects like dizziness and drowsiness. This study tests whether delivering pregabalin through the skin using ultrasound (phonophoresis), combined with calf muscle stretching (Muscle Energy Technique), can reduce nerve pain and improve walking better than ultrasound alone.

This description comes directly from the study's public registry record.

Talk to the study team

Dr. Muhammad Muneeb Jafar, Doctor of Physical Therapy  ·  +92 312 7000616  ·  muneebjafar.DPT@tuf.edu.pk

Dr Muhammad Ateeb, PhD Public Health  ·  +923357333383  ·  mateeb.oric@tuf.edu.pk

Always discuss trial participation with your own doctor first.

Locations (1)

The University of FaisalabadFaisalābad, Punjab Province, PakistanRecruiting

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Source record: clinicaltrials.gov/study/NCT07598474