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Study identifier: NCT07598435 Synced from ClinicalTrials.gov · July 29, 2026
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Rhythmic Initiation vs Isometric Training for Arm Recovery After Stroke

Condition: Stroke · Upper Extremity Paresis  ·  Sponsor: University of Faisalabad

PhaseNA
Planned participants40
Who can joinAll sexes, 40 Years to 60 Years
Healthy volunteersNo

About this study

Stroke is a leading cause of long-term disability worldwide. Many stroke survivors experience persistent weakness, loss of motor control, and poor coordination in their upper limb, which limits their ability to perform daily activities and return to independent living. This study compares two physical therapy approaches for patients in the subacute stage of stroke recovery (1 to 6 months after stroke). The first approach is Rhythmic Initiation, a technique from Proprioceptive Neuromuscular Facilitation (PNF) that uses smooth, guided movement patterns progressing from passive to active movement. The second approach is Isometric Resistance Training, which involves holding static muscle contractions against resistance without moving the joint. The study will enroll 40 patients aged 40 to 60 years with unilateral upper limb weakness from a first-time stroke. Participants will be randomly assigned to receive either Rhythmic Initiation or Isometric Resistance Training for 30 minutes per session, 5 days per week, for 4 weeks. The researchers will measure changes in motor function, muscle strength, coordination, and spasticity before and after the 4-week intervention. The results will help physiotherapists understand which approach is more effective for upper limb rehabilitation in subacute stroke patients.

This description comes directly from the study's public registry record.

Talk to the study team

Dr Marium Zafar, MS-NMPT  ·  +92 300 4561972  ·  mariumzafar.dpt@tuf.edu.pk

Dr Muhammad Ateeb, PhD Public Health  ·  +923357333383  ·  mateeb.oric@tuf.edu.pk

Always discuss trial participation with your own doctor first.

Locations (1)

The University of FaisalabadFaisalābad, Punjab Province, PakistanRecruiting

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Source record: clinicaltrials.gov/study/NCT07598435