Condition: Sepsis and Septic Shock · Sponsor: Insel Gruppe AG, University Hospital Bern
Sepsis-induced immunosuppression (SIS) is a common complication in patients with septic shock. Reduced expression of Human leukocyte antigen isotype DR (HLA-DR) on circulating monocytes is a marker for SIS and correlates with risk of secondary infections and mortality. The miRSep study aims to improve the understanding of early microRNA (miRNA) mediated changes in HLA-DR on monocytes in patients with septic shock.
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| Inselspital | Bern, Switzerland | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07597122