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Study identifier: NCT07596576 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Sheba Healthspan Research Population (SHARP) Trial - Sheba Longevity Center Diagnostic and Intervention Protocol to Lower Biological Age in Older Adults

Condition: Healthy Aging · Healthspan · Biological Age  ·  Sponsor: Sheba Medical Center

PhaseNA
Planned participants1500
Who can joinAll sexes, 50 Years to no upper limit
Healthy volunteersYes

About this study

Background: Population aging is accelerating rapidly in Israel and worldwide, necessitating adaptation of the healthcare system and considering new approaches that serve the needs of older adult populations. Working hypothesis and aims: We hypothesize that a personalized health and behavior intervention program will decrease the biological age as assessed by several biological aging clocks and improve functional and cognitive performance among older adults. Methods: We propose to conduct a randomized study among healthy community-dwelling elderly subjects (\>50 years old). The study will include an extensive aging assessment and imaging protocol (baseline assessment), including comprehensive physical, functional, sensory, cognitive, and mental assessment. Each participant in the intervention group will receive a personalized intervention program based on an integrative systems approach analysis. In addition, a uniquely developed application will track compliance and monitor physiological data through a provided wearable device. The control group will be assessed at baseline without receiving an intervention program. Each participant will visit the center aging after 6 months for a blood test and after 12 months for a second extensive diagnostic protocol, similar to the baseline assessment protocol. About 1,500 subjects will be recruited to participate in the study. Expected results: Obtaining data at two points will allow us to examine efficiency and compliance with a pers…

This description comes directly from the study's public registry record.

Talk to the study team

tzipi strauss, MD  ·  972526664446  ·  zipora.strauss@sheba.heath.gov.il

evelyne bischof, MD PhD  ·  972512504301  ·  bischofevelyne@gmail.com

Always discuss trial participation with your own doctor first.

Locations (1)

Sheba Medical CenterRamat Gan, Tel Aviv, IsraelRecruiting

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Source record: clinicaltrials.gov/study/NCT07596576