Condition: Advanced Colon Adenocarcinoma · Advanced Colorectal Adenocarcinoma · Advanced Rectal Adenocarcinoma · Sponsor: City of Hope Medical Center
This phase II trial tests how well giving botensilimab and balstilimab prior or to surgery (neoadjuvent) works for the treatment of colorectal cancer that may have spread from where it first started to nearby tissue, lymph nodes, or distant parts of the body (advanced) and that can be removed by surgery (resectable) colorectal cancer. Immunotherapy with monoclonal antibodies, such as botensilimab and balstilimab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Giving botensilimab and balstilimab before surgery may make the tumor smaller. Giving neoadjuvant botensilimab and balstilimab may be effective for the treatment of advanced resectable colorectal cancer.
This description comes directly from the study's public registry record.
Sebastian Perez · 6262184357 · sebperez@coh.org
Always discuss trial participation with your own doctor first.
| CTCA at Western Regional Medical Center | Goodyear, Arizona, United States | Recruiting |
| City of Hope Corona | Corona, California, United States | Recruiting |
| City of Hope Medical Center | Duarte, California, United States | Recruiting |
| City of Hope Seacliff | Huntington Beach, California, United States | Recruiting |
| City of Hope at Irvine Lennar | Irvine, California, United States | Recruiting |
| City of Hope at Long Beach Elm | Long Beach, California, United States | Recruiting |
| City of Hope South Pasadena | South Pasadena, California, United States | Recruiting |
| City of Hope Upland | Upland, California, United States | Recruiting |
| City of Hope Atlanta Cancer Center | Newnan, Georgia, United States | Recruiting |
| City of Hope at Illinois Chicago Downtown | Chicago, Illinois, United States | Recruiting |
| City of Hope at Chicago | Zion, Illinois, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07595874