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Study identifier: NCT07594821 Synced from ClinicalTrials.gov · July 29, 2026
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MeDe Study: Comparing Median Nerve Decompression at the Carpal Tunnel Alone Versus Median Nerve Decompression at Both the Carpal Tunnel and Lacertus Fibrosis in Adults With Carpal Tunnel Syndrome

Condition: Carpal Tunnel Syndrome (CTS) · Lacertus Syndrome  ·  Sponsor: Maasstad Hospital

PhaseNA
Planned participants110
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Carpal tunnel syndrome (CTS) is a condition that can cause pain, numbness, or tingling in the hand and wrist. The most common surgery for CTS is called carpal tunnel release, which aims to relieve pressure on the main nerve in the wrist. However, after this surgery, some patients (up to 4 out of 10) still have symptoms, and about 1 in 8 may need another surgery. One reason symptoms can continue is that the nerve may also be compressed higher up in the arm, near a ligament called the Lacertus fibrosus. Releasing this area might help, but it is often not checked or treated during the first surgery because current tests (like physical exams, nerve studies, and ultrasounds) cannot reliably detect it. This study is comparing two approaches for people with CTS: 1. Standard surgery - only releasing the carpal tunnel. 2. Extended surgery - releasing both the carpal tunnel and the Lacertus fibrosus. The goal is to see which surgery helps patients feel better and have fewer symptoms in the hand and wrist after treatment.

This description comes directly from the study's public registry record.

Talk to the study team

Sebastian Poggio Voormolen, BSc, PhD candidate  ·  +31 6 46560865  ·  PoggioVoormolenS@maasstadziekenhuis.nl

Always discuss trial participation with your own doctor first.

Locations (2)

Maasstad ZiekenhuisRotterdam, South Holland, NetherlandsRecruiting
Spijkenise Medisch CentrumRotterdam, South Holland, NetherlandsRecruiting

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Source record: clinicaltrials.gov/study/NCT07594821