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Study identifier: NCT07592260 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

OptiMAx Will Test Whether SQ-LNS Incentivises Vaccination Uptake in Rural Chad and Niger, With a Cost Effectiveness Analysis. It Will Also Look at Whether Having Received SQ-LNS Before Becoming Malnourished Leads to Better Outcomes for Children Treated Under the OptiMA Protocol.

Condition: Malnutrition Severe · Vaccination  ·  Sponsor: Alliance for International Medical Action

PhaseNA
Planned participants20000
Who can joinAll sexes, 6 Months to 59 Months
Healthy volunteersYes

About this study

Malnutrition and infectious disease form a vicious circle, posing a double threat to vulnerable children in low- and middle-income countries. Malnutrition makes children more vulnerable to infectious diseases, while infectious diseases increase the risk of malnutrition. When caught in this cycle, children are far more likely to die or suffer adverse effects on their health and development. High rates of wasting and low immunization coverage also constitute a weakening double burden for already fragile health systems. Every year in these contexts, hundreds of thousands of children are treated for severe wasting, while at the same time suffering repeated and prolonged epidemics of vaccine-preventable diseases such as measles. Rural areas of Chad and Niger are at the heart of this dynamic, recording some of the worst indicators of malnutrition and low vaccination coverage rates. Small-quantity lipid-based nutritional supplements (SQ-LNS) are a category of ready-to-use, nutrient-dense food supplements fortified with micronutrients, designed to prevent malnutrition and improve child survival, growth and development. A recent meta-analysis on SQ-LNS reveals that giving a child just one sachet of SQ-LNS a day for a year can reduce the risk of mortality by 27%, iron-deficiency anemia by 64%, severe wasting by 31% and severe stunting by 17%. The recent World Health Organization (WHO) guideline on complementary feeding of infants and young children aged 6 to 23 months recently recomme…

This description comes directly from the study's public registry record.

Talk to the study team

Kevin Phelan, MSc  ·  +33 664235628  ·  kevin.phelan@alima.ngo

Susan Shepherd, MD  ·  9292257735  ·  susan.shepherd@alima.ngo

Always discuss trial participation with your own doctor first.

Locations (2)

Ngouri hospitalNgouri, Lac Region, ChadRecruiting
Mirriah hospitalMirriah, Zinder Region, NigerRecruiting

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Source record: clinicaltrials.gov/study/NCT07592260