Condition: Diabete Type 1 · Chronic Kidney Disease · Sponsor: University of Chicago
Single arm- subject treated with Tegoprubart and everolimus. The purpose of this research is to gather information on the safety and effectiveness of investigational regimen containing 2 experimental components: * An investigational drug called Tegoprubart and * Human pancreatic islet cells Both Tegoprubart and human pancreatic islet cells are considered investigational because they are not approved for use in the United States by the Food and Drug Administration (FDA). Participation in this research will last about 5 years. Assess safety, tolerability, and efficacy of transplanted islet cells and immunomodulation with Tegoprubart in combination with anti-thymocyte globulin (ATG), etanercept and with everolimus in adults with brittle T1D and chronic kidney disease (stage 2-3a).
This description comes directly from the study's public registry record.
Alexandra Grange - Islet Cell Transplant Program Manager · 773-702-9771 · Alexandra.Grange@bsd.uchicago.edu
Minelly Escobedo · Minelly.Escobedo@bsd.uchicago.edu
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| The University of Chicago | Chicago, Illinois, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07592000