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Study identifier: NCT07590102 Synced from ClinicalTrials.gov · July 29, 2026
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A Study to Investigate the Effect of the CYP3A Inducer Phenytoin and the CYP3A Inhibitor Itraconazole on the Pharmacokinetics of BGB-58067 in Healthy Participants

Condition: Healthy Volunteers  ·  Sponsor: BeOne Medicines

PhasePhase 1
Planned participants30
Who can joinAll sexes, 18 Years to 65 Years
Healthy volunteersYes

About this study

This study is being done to understand how the body processes the study drug (BGB-58067) when it is taken together with other medicines. BGB-58067 is mainly broken down in the body by a liver enzyme called CYP3A. Some medicines can affect how this enzyme works. For example, certain medicines can increase the production of the enzyme (called inducers), while others can block or inhibit its activity (called inhibitors). This may change how much of the study drug is present in the bloodstream. In this study, we will give BGB-58067 together with two commonly used medicines: * Part A: Phenytoin (inducer), which can increase the production of the enzyme, and * Part B: Itraconazole (inhibitor), which can inhibit the activity of the enzyme.

This description comes directly from the study's public registry record.

Talk to the study team

Study Director  ·  1-877-828-5568  ·  clinicaltrials@beonemed.com

Always discuss trial participation with your own doctor first.

Locations (1)

Cmax Clinical ResearchAdelaide, South Australia, AustraliaRecruiting

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Source record: clinicaltrials.gov/study/NCT07590102