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Study identifier: NCT07589595 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Study of Donanemab (LY3002813) in Participants With Early Cognitive Decline (TRAILBLAZER-ALZ 7)

Condition: Cognitive Dysfunction · Lewy Body Disease · Synucleinopathies  ·  Sponsor: Eli Lilly and Company

PhasePhase 2
Planned participants350
Who can joinAll sexes, 55 Years to 85 Years
Healthy volunteersNo

About this study

The main purpose of this study is to evaluate whether treatment with donanemab slows the progression of cognitive (how we think, learn, remember, pay attention, and make decisions) and functional (how we are able to perform daily activities) decline. For each participant, the study will last one and a half years.

This description comes directly from the study's public registry record.

Talk to the study team

Trial questions or participation questions: 1-877-CTLILLY (1-877-285-4559) or  ·  1-317-615-4559  ·  LillyTrials@Lilly.com

Physicians interested in becoming principal investigators please contact  ·  clinical_inquiry_hub@lilly.com

Always discuss trial participation with your own doctor first.

Locations (72)

TrialSphere CorpChandler, Arizona, United StatesRecruiting
HonorHealth Research InstituteScottsdale, Arizona, United StatesNot Yet Recruiting
Profound Research LLCCarlsbad, California, United StatesNot Yet Recruiting
Irvine Clinical ResearchIrvine, California, United StatesRecruiting
UCSD - Altman Clinical and Translational Research Institute (ACTRI)La Jolla, California, United StatesNot Yet Recruiting
Stanford Neuroscience Health CenterPalo Alto, California, United StatesNot Yet Recruiting
CenExel Rocky Mountain Clinical ResearchEnglewood, Colorado, United StatesNot Yet Recruiting
Ki Health Partners, LLc, dba New England Institute for Clinical ResearchStamford, Connecticut, United StatesNot Yet Recruiting
JEM Research InstituteAtlantis, Florida, United StatesRecruiting
VIN - AventuraAventura, Florida, United StatesRecruiting
Brain Matters ResearchDelray Beach, Florida, United StatesRecruiting
Neuropsychiatric Research Center of Southwest FloridaFort Myers, Florida, United StatesRecruiting

+ 60 more locations — full list on the registry record.

Follow this study

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Source record: clinicaltrials.gov/study/NCT07589595