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Study identifier: NCT07588503 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

FES Cycling With BFR in the Spinal Cord Injury Population

Condition: Spinal Cord Injury · Cardio Vascular Disease · Metabolic Diseases, Type 2 Diabetes, Cardiovascular Disease  ·  Sponsor: Dr. B. Catharine. Craven

PhasePhase 1
Planned participants6
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

Cardiometabolic Disease (CMD) is the silent killer within the spinal cord injury/disease (SCI/D) population. Many SCI/D patients' initial CMD presentation is with a heart attack, stroke, or sudden cardiac death, highlighting the need for interventions to reduce CMD risk. CMD contributes to 46% of deaths, with 30-50% of the SCI/D population living with undiagnosed CMD. Treating CMD risk is more challenging in the SCI/D population due to prolonged inactivity, inability to exercise, and excessive caloric intake to expenditure ratio. Identifying accessible and inclusive strategies to combat CMD risk in the SCI/D population is a compelling and urgent health priority. Blood flow restriction (BFR) exercise involves applying inflatable cuffs to the proximal end of an individual's limbs. Changes to the amount of blood flowing into and out of the limb lead to a low oxygen environment within the limb, shifting the way the muscles can produce the energy required to function, increasing the benefits of low- and moderate-intensity exercise. Coupling BFR with Functional electrical stimulation cycling (FES-cycling), a commonly used rehabilitation tool within the SCI population, could improve FES-cycling's short- and long-term benefits without reducing the accessibility and inclusiveness of long-term exercise prescription. Although preliminary BFR research in the SCI/D has identified positive muscular improvements, whether FES-cycling coupled with BFR can be safely prescribed or feasibly imp…

This description comes directly from the study's public registry record.

Talk to the study team

Thomas P Walden, Ph.D  ·  4165973422  ·  thomas.walden@uhn.ca

Katherine Chan, MSc  ·  4165973422  ·  Katherine.chan@uhn.ca

Always discuss trial participation with your own doctor first.

Locations (1)

Lyndhurst CentreToronto, Ontario, CanadaRecruiting

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Source record: clinicaltrials.gov/study/NCT07588503