Condition: Appendiceal Cancer · Appendiceal Adenocarcinoma · Sponsor: City of Hope Medical Center
This study investigates integrated epigenetic and epitranscriptomic features of appendiceal cancer using archived tumor tissue specimens from the same patient cohort. The study includes DNA methylation profiling and m6A epitranscriptomic profiling to define molecular subtypes, evaluate associations with clinicopathologic features, and develop molecular risk scores for prognostic stratification. The primary goal is to determine whether DNA methylation- and m6A-based molecular features can complement conventional histopathologic grading and improve risk stratification.
This description comes directly from the study's public registry record.
Ajay Goel · 6262184673 · ajgoel@coh.org
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| City of Hope Medical Center | Durate, California, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07587268