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Study identifier: NCT07585760 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

CM336 Plus Isatuximab for Newly Diagnosed Multiple Myeloma With Renal Impairment

Condition: Multiple Myeloma (MM) · Multiple Myeloma Light Chain Induced Renal Insufficiency  ·  Sponsor: Institute of Hematology & Blood Diseases Hospital, China

PhasePhase 2
Planned participants26
Who can joinAll sexes, 18 Years to 80 Years
Healthy volunteersNo

About this study

This study is a single-center, single-arm, open-label, Phase II interventional clinical trial designed to evaluate the efficacy and safety of a CM336 and isatuximab regimen in patients with newly diagnosed multiple myeloma (NDMM) accompanied by renal impairment (\[eGFR\] \< 40 mL/min). Enrolled subjects will receive three consecutive cycles of induction therapy with CM336 in combination with isatuximab.

This description comes directly from the study's public registry record.

Talk to the study team

Gang An, PhD & MD  ·  +86 13502181109  ·  angang@ihcams.ac.cn

Always discuss trial participation with your own doctor first.

Locations (1)

Institute of Hematology and Blood Diseases Hospital Chinese Academy of Medical SciencesTianjin, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07585760