Condition: Non Celiac Wheat Sensitivity · IBS (Irritable Bowel Syndrome) · Functional Dyspepsia · Sponsor: University of Palermo
Over 50% of non-celiac wheat sensitivity (NCWS) patients are HLA DQ2/DQ8 positive and often have a Celiac Disease (CD) family history. Studies have identified a subgroup of NCWS patients whose clinical and immunological features are closer to CD than to irritable bowel syndrome/functional dyspepsia (IBS/FD) ('inflammatory subgroup'). The investigators hypothesized that among CD patient's relatives, there might be a high number of NCWS subjects, who hypothetically belong to the 'inflammatory subgroup'. Therefore, the aim of this multi-step project is to identify the prevalence of both self-reported NCWS and IBS/FD not related to wheat ingestion among CD patient's relatives (parents, grandparents, siblings and sons).
This description comes directly from the study's public registry record.
Pasquale Mansueto, MD · +393477279879 · pasquale.mansueto@unipa.it
Aurelio Seidita, MD · aurelio.seidita@unipa.it
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| Celiac Disease and Food Intolerance Clinic, Geriatrics Unit, "P. Giaccone" University Hospital, Palermo | Palermo, PA, Italy | Recruiting |
| Internal Medicine Unit, P.O. "V. Cervello," Ospedali Riuniti "Villa Sofia-Cervello," Palermo | Palermo, PA, Italy | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07584473