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Study identifier: NCT07584278 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Probiotics and Biomarkers in Irritable Bowel Syndrome

Condition: Irritable Bowel Syndrome (IBS)  ·  Sponsor: Sahlgrenska University Hospital

PhaseNA
Planned participants252
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this double-blind parallel-arm randomized controlled trial is to learn if a probiotic supplement (containing a new strain derived from L. reuteri) alters outcomes related to symptom severity and transit time in adults with irritable bowel syndrome (IBS). The main question it aims to answer is: Does the probiotic alter IBS symptom severity? Researchers will compare the probiotic to a placebo (a lookalike substance that contains no probiotic) to see if the probiotic works to alter outcomes. Participants will: Be randomized to either take the probiotic supplement or placebo supplement daily for 12 weeks. Visit the lab for 4 study visits (visit 1: screening and informed consent; visit 2: randomization, data collection, beginning the intervention; visit 3: end of intervention and data collection; visit 4: 3 month post intervention follow up and data collection). Provide biological samples (blood, stool, saliva, urine) Complete questionnaires

This description comes directly from the study's public registry record.

Talk to the study team

Magnus Simren, MD, PhD  ·  0046313428107  ·  magnus.simren@medicine.gu.se

MagTarmlab office  ·  0046313428107  ·  magtarmlab.su@vgregion.se

Always discuss trial participation with your own doctor first.

Locations (1)

Mag-tarmlab, Sahlgrenska University HospitalGothenburg, SwedenRecruiting

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Source record: clinicaltrials.gov/study/NCT07584278